Combinatorial Chemistry & High Throughput Screening

Author(s): Jurgen Zindel

DOI: 10.2174/138620705774575418

Automated Synthesis & Purification at Bayer CropScience Chemistry Frankfurt

Page: [631 - 635] Pages: 5

  • * (Excluding Mailing and Handling)

Abstract

The Automated Synthesis & Purification team at Bayer CropScience in Frankfurt provides services and support in the areas of synthesis and post synthesis activities for chemists. This article describes our workflow and the special robotic systems used. We produce small to medium sized compound libraries using liquid phase techniques. An example of a compound library taken from the herbicide area is given.

Keywords: solid phase extraction, liquid-liquid extraction, HPLC, AMINOTRIAZINES, 2-amino-4-chloro-triazine synthons