Author(s): Konstantinos Daniilides, Nikolaos Lougiakis, Nicole Pouli, Panagiotis Marakos, Pinelopi Samara and Ourania Tsitsilonis
Page: [619 - 627] Pages: 9
* (Excluding Mailing and Handling)
A number of new aminosubstituted benzofuran analogues have been prepared and their cytotoxic/cytostatic activity was investigated against five human tumor cell lines (MCF-7, SKBR3, SKOV3, HCT-116 and HeLa). Certain compounds showed noticeable tumor cell growth inhibition, indicative of possible structure-activity relationships.
Keywords: Benzofurans, Cytotoxicity, Heterocycles, Sonogashira cross-coupling, Wadsworth-Emmons reaction.
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