Combinatorial Chemistry & High Throughput Screening

Author(s): Faramarz Rostami-Charati, Mohammad R. Hosseini-Tabatabaei and Mehdi Shahraki

DOI: 10.2174/13862073113169990037

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A Facile One-Pot Synthesis of Functionalized 1,3-Oxathiolan-2-Yliden Derivatives: Multicomponent Reaction of Oxiranes in Water

Page: [35 - 37] Pages: 3

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Abstract

An efficient synthesis of 1,3-oxathiolan-2-yliden derivatives is described via a simple reactions between CHacids, CS2 and oxiranes in the presence of triethylamine at 70oC in water as the solvent. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of this method.

Keywords: 1, 3-oxathiolan-2-yliden, one-pot reactions, oxirane, triethylamine.