Current Vascular Pharmacology

Author(s): Maria Sarigianni, Konstantinos Dimitrakopoulos and Apostolos Tsapas

DOI: 10.2174/157016111203140518173019

Non-dipping Status in Arterial Hypertension: An Overview

Page: [527 - 536] Pages: 10

  • * (Excluding Mailing and Handling)

Abstract

Non-dipping is a common pattern of arterial hypertension and it is associated with increased cardiovascular risk. Use of ambulatory blood pressure monitoring, as suggested in recent guidelines, could further increase its prevalence among subjects with hypertension. In this review we discuss assessment, relevance and associated factors. Non-dipping could be addressed through chronotherapy, the use of specific classes of anti-hypertensives, such as renin-angiotensin blockers, or modification of associated factors. However, more data are needed in order to comprehensively estimate factors associated with non-dipping and how they could be modified.

Keywords: Arterial hypertension, ambulatory blood pressure monitoring, blood pressure, cardiovascular risk factor, chronotherapy, night time blood pressure, non-dipping.