Abstract

Adenovirus vectors belong to the most frequently used vector type in gene therapy approaches. In addition, adenovirus vector particles and adenovirus subviral particles offer a great potential for the direct delivery of proteins into cells. In this review we discuss this potential and the technology of adenovirus as a protein delivery platform for applications ranging from vaccination to gene therapy.

Keywords: Protein delivery, adenovirus vector, adenovirus subviral particles, peptide delivery, gene transfer vectors, vector capsids, epidermal growth factor, endosomal