Combinatorial Chemistry & High Throughput Screening

Author(s): Samad Khaksar and Hasan Zakeri

DOI: 10.2174/138620712801619203

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Pentafluorophenylammonium Triflate as a Mild and New Organocatalyst for Acylation of Alcohols, Phenols, and Amines Under Solvent-Free Condition

Page: [576 - 579] Pages: 4

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Abstract

A simple, inexpensive, environmentally friendly and efficient route for the acylation of a number of alcohols, phenols and amines using pentafluorophenylammonium triflate (PFPAT) as a catalyst is described. PFPAT organocatalyst is air-stable, cost-effective, easy to handle, and easily removed from the reaction mixtures.

Keywords: Alcohols, organocatalyst, pentafluorophenylammonium triflate, phenol, Amines, Solvent-Free, acylation, PFPAT, chemoselectivity, chemical transformations