Author(s): Irene L. Doering and Elmar Richter
Page: [83 - 86] Pages: 4
* (Excluding Mailing and Handling)
Myosmine, a minor tobacco alkaloid widely occurring in food products of plant and animal origin, inhibits the conversion of testosterone to estradiol by human aromatase (IC50: 33±2 μM) sevenfold more potent than nicotine (IC50: 223±10 μM) and may have implications for sexual hormone homoeostasis.
Keywords: CYP19, cytochrome P450, human aromatase, myosmine, nicotine
