Author(s): R. G. Fumarel, P. Alber, A. Hurduc, N. Stafidov and M. L. Pascu
Page: [98 - 101] Pages: 4
* (Excluding Mailing and Handling)
Methotrexate (MTX) use associated with optical irradiation of the malignant tumours requires knowledge of its intratumoral retention time. Radioactive Chromatography and absorption spectroscopy confirm synthesizing of 2,4 diamino 6-pertechnetate pterine that pursues MTX biodistribution. Sequential scintigraphy shows an intratumoral MTX retention time of one hour from systemic administration in bolus.
Keywords: Methotrexate, Photosensitiser, Radioactive labelling, Radioactive chromatography, Gel filtration, Scintigraphy
Download PDF Flyer