Author(s): J. Morgan, R. Haritakul and P. A. Keller
Page: [277 - 280] Pages: 4
* (Excluding Mailing and Handling)
A series of 2,4- and 4,6-diaminopyrimidines were prepared and evaluated for their in vitro antimalarial activity. Of the 12 compounds tested 7 showed reasonable activity with 1 having a sub-micromolar IC50.
Keywords: Antimalarial, Diaminopyrimidine, Structure-activity relationship
Download PDF Flyer