Author(s): Nettis Eustachio, Colanardi Maria Cristina and Ferrannini Antonio
Page: [300 - 307] Pages: 8
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Cyclosporin A (CsA) is a fungal metabolite that has immunomodulatory and anti-inflammatory effects. Cyclosporin binds to cyclophilin, inhibiting CD4-T-cell activation. In this paper we discuss the mechanism of action of CsA and its role as a novel approach for the treatment of allergic disease.
Keywords: allergic contact dermatitis, asthma, atopic dermatitis, cyclosporin, ocular allergic diseases, urticaria
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