Letters in Drug Design & Discovery

Author(s): V. M. Victor

DOI: 10.2174/1570180053765219

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Ascorbic Acid as Modulator of Immune Function in Sepsis

Page: [239 - 244] Pages: 6

  • * (Excluding Mailing and Handling)

Abstract

Oxidative stress is a major contributing factor to high mortality rates associated with several diseases such as sepsis. This condition can be controlled to a certain degree by antioxidants for instance ascorbic acid (vitamin C). This review focuses on the potential treatment of sepsis by ascorbic acid and its effects on the immune cell function.

Keywords: ascorbic acid, sepsis, oxidative stress, lipopolysaccharide, free radicals, immune cells