The current antiretroviral regimens in the long run, can lead to poor adherence to treatment, to emergence of resistant viral strains and different adverse effects limiting benefits of HAART. A variety of novel treatment strategies have been proposed to help the long-term management of HAART. The principal innovative therapeutic strategies under investigation will be discussed: treatment simplification, once daily regimens, structured or response guided treatment interruptions and proactive antiretroviral switching.
Keywords: hiv, aids, haart, hiv treatment new strategies