Abstract

Oleoylethanolamide is an endogenous lipid mediator that reduces food intake and decreases body weight gain in rodents. As in leptin, oleoylethanolamide has a central and peripheral anorexic effect. In this article, we describe common potential targets, suggesting a molecular cross-talk between leptin and oleoylethanolamide which may regulate feeding behaviour.

Keywords: Oleoylethanolamide (OEA), Leptin, Obesity, Anorexigenic, Feeding behaviour, Anti-obesity effects, Rats