Combinatorial Chemistry & High Throughput Screening

Author(s): Nana Liang and Bin Zhang

DOI: 10.2174/138620711794728761

Impact of Nanomaterials on High Throughput Separation Methodologies

Page: [182 - 190] Pages: 9

  • * (Excluding Mailing and Handling)

Abstract

Due to the unique properties, such as their large surface to volume ratio and easy modification, nanomaterials have recently been studied as effective sorbents in the field of separation science. It has proven to be more effective and efficient to use nanoparticles (NPs) as a stationary phase in solid-phase extraction separation. In addition, NPs can be also used as buffer additives in capillary electrophoresis separation. This review highlights recent developments in High throughput separation methodologies employing nanomaterials such as carbon nanotubes, gold nanoparticles and magnetic NPs etc.

Keywords: Nanomaterials, nanoparticles, high throughput separation, solid-phase extraction, microchip solid phase extraction, capillary electrophoresis, high-performance liquid chromatography, recombinant, polymerase chain reaction, fluorescent dyes, drug metabolites, Separation Methodologies, DNA separations