Abstract

In the family of biologically active heterocyclic templates, quinoxalines, quinoxalinones, and quinoxalinols have received much attention owing to a wide range of their biological activities. As a consequence, approaches to the combinatorial synthesis of these compounds were surveyed, and this review discusses the solid-phase, solution-phase, solvent-free, and microwave-assisted parallel synthesis of quinoxalines, quinoxalinones, and quinoxalinols.

Keywords: Quinoxaline, quinoxalinone, quinoxalinol, heterocycle, solid-phase, solution-phase, solvent-free, microwave irradiation