Combinatorial Chemistry & High Throughput Screening

Author(s): Alberto Coelho, Abel Crespo, Franco Fernandez, PierFrancesco Biagini, Angela Stefanachi and Eddy Sotelo

DOI: 10.2174/138620708786734253

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Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine

Page: [843 - 847] Pages: 5

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Abstract

Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.

Keywords: Supported reagents, TMG, base