Search Result "microsome test"


Evaluation of Microsomal Incubation Conditions on CYP3A4-Mediated Metabolism of Cyclosporine A by a Statistical Experimental Design

Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 265-271
Author(s): Monica Hermann, Eili T. Kase, Espen Molden, Hege Christensen

CYP1A1 Is a Major Enzyme Responsible for the Metabolism of Granisetron in Human Liver Microsomes

Journal: Current Drug Metabolism
Volume: 6 Issue: 5 Year: 2005 Page: 469-480
Author(s): H. Nakamura, N. Ariyoshi, K. Okada, H. Nakasa, K. Nakazawa, M. Kitada

In Vitro Microsomal Hepatic Metabolism of Antiasthmatic Prototype LASSBio-448

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 11 Year: 2014 Page: 1388-1398
Author(s): Isabelle Karine Costa Nunes,Luzineide Wanderley Tinoco,Helvecio Martins-Junior,Claudia Rezende,Eliezer J. Barreiro,Lidia Moreira Lima

Microsomal Prostaglandin E Synthase: A Key Enzyme in PGE2 Biosynthesis and Inflammation

Journal: Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents
Volume: 1 Issue: 3 Year: 2002 Page: 167-175
Author(s): P- J. Jakobsson, D. Engblom, A. Ericsson-Dahlstrand, A. Blomqvist

Applications of High Throughput Microsomal Stability Assay in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 6 Year: 2008 Page: 469-476
Author(s): Li Di, Edward H. Kerns, Xuewen JoAnn Ma, Youping Huang, Guy T. Carter

Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott

Future Challenges for Microsomal Transport Protein Inhibitors

Journal: Current Vascular Pharmacology
Volume: 7 Issue: 3 Year: 2009 Page: 277-286
Author(s): Anthony S. Wierzbicki, Tim Hardman, William T. Prince

Research Article

Effects of Asphodeline lutea Compounds on Toxicity Models in Isolated Rat Microsomes and Hepatocytes

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 3 Year: 2018 Page: 251-255
Author(s): Magdalena Kondeva-Burdina,Rumyana Simeonova,Vessela Vitcheva,Irina Lazarova,Reneta Gevrenova,Dimitrina Zheleva-Dimitrova,Gokhan Zengin,Nikolay D. Danchev

Effects of Propofol Analogs on Glucuronidation of Propofol, an Anesthetic Drug, by Human Liver Microsomes

Journal: Drug Metabolism Letters
Volume: 1 Issue: 1 Year: 2007 Page: 77-79
Author(s): Makiko Shimizu, Yoshiaki Matsumoto, Hiroshi Yamazaki

Inhibition of Cytochrome P450 1A2-Mediated Metabolism and Production of Reactive Oxygen Species by Heme Oxygenase-1 in Rat Liver Microsomes

Journal: Drug Metabolism Letters
Volume: 5 Issue: 1 Year: 2011 Page: 6-16
Author(s): James R. Reed, George F. Cawley, Wayne L. Backes

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