Search Result "microdosing approach"


Microdosing, Imaging Biomarkers and SPECT: A Multi-Sided Tripod to Accelerate Drug Development

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 9 Year: 2009 Page: 928-934
Author(s): Ernest K.J. Pauwels, Kim Bergstrom, Giuliano Mariani, Kalevi Kairemo

Research Article

Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer’s-like Amyloidosis

Journal: Current Alzheimer Research
Volume: 15 Issue: 1 Year: 2018 Page: 1220-1230
Author(s): Edward N. Wilson,Sonia Do Carmo,M. Florencia Iulita,Hélène Hall,Grant L. Austin,Dan T. Jia,Janice C. Malcolm,Morgan K. Foret,Adam R. Marks,D. Allan Butterfield,A. Claudio Cuello

Positron Emission Tomography for Future Drug Development

Journal: Recent Patents on Medical Imaging
Volume: 1 Issue: 2 Year: 2011 Page: 137-151
Author(s): Ryogo Minamimoto, Chumpol Theeraladanon, Akiko Suzuki, Tomio Inoue

Research Article

Targetability and Biodistribution of Radioiodinated Hypericin: Comparison between Microdosing and Carrier-Added Preparations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 6 Year: 2014 Page: 852-861
Author(s): Marlein Miranda Cona,Junjie Li,Yuanbo Feng,Feng Chen,Alfons Verbruggen,Peter de Witte,Raymond Oyen,Yicheng Ni

The Application of PET Technique for the Development and Evaluation of Novel Antipsychotics

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 3 Year: 2010 Page: 371-377
Author(s): Akihiro Takano

The Metabolism of Anticancer Drugs by the Liver: Current Approaches to the Drug Development Process

Journal: Current Drug Metabolism
Volume: 16 Issue: 7 Year: 2015 Page: 506-521
Author(s): Mariusz Belka,Tomasz Baczek

Radiolabeled Compounds in the Development of Cytotoxic Agents

Journal: Current Pharmaceutical Design
Volume: 10 Issue: 2 Year: 2004 Page: 2923-2934
Author(s): Kalevi J.A. Kairemo, Marja Tahtinen

Methods to Assess Tissue-Specific Distribution and Metabolism of Drugs

Journal: Current Drug Metabolism
Volume: 5 Issue: 6 Year: 2004 Page: 463-481
Author(s): Oliver Langer, Markus Muller

Structural Biology Toward Rational Drug Development in Collaboration with Molecular Imaging

Journal: Current Medical Imaging Reviews
Volume: 8 Issue: 4 Year: 2012 Page: 308-313
Author(s): Takashi Umehara, Mikako Shirouzu, Shigeyuki Yokoyama

Application of Liquid Chromatography-Accelerator Mass Spectrometry (LC-AMS) to Evaluate the Metabolic Profiles of a Drug Candidate in Human Urine and Plasma

Journal: Drug Metabolism Letters
Volume: 1 Issue: 3 Year: 2007 Page: 226-231
Author(s): Chandra Prakash, Christopher L. Shaffer, Larry M. Tremaine, Rosa G. Liberman, Paul L. Skipper, Jimmy Flarakos, Steven R. Tannenbaum

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