Search Result "metabolic clearance"


Research Article

The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles

Journal: Drug Metabolism Letters
Volume: 14 Issue: 2 Year: 2021 Page: 126-136
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao

Prediction of Human Hepatic Clearance Using an In Vitro Plated Hepatocyte Clearance Model

Journal: Drug Metabolism Letters
Volume: 3 Issue: 4 Year: 2009 Page: 296-307
Author(s): Piyun Chao, Jeffrey Barminko, Eric Novik, Yi Han, Timothy Maguire, K.-C. Cheng

A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds

Journal: Drug Metabolism Letters
Volume: 10 Issue: 1 Year: 2016 Page: 3-15
Author(s): Chi-Chi Peng,Utkarsh Doshi,Chandra Prakash,Albert P. Li

Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

Calculating the Metabolic Clearance of a Mother Substance from the Clearance of its Analogue Tracer Measured by PET

Ebook: Functional Molecular Imaging In Hepatology
Volume: 1 Year: 2012
Author(s): Ludvik Bass,Michael Sørensen,Ole Lajord Munk,Susanne Keiding
Doi: 10.2174/978160805290511201010032

In Vitro Screening of Metabolic Clearance Using Two Concentration Points

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 233-240
Author(s): Eric T. Williams, Nadia Farah, Robert D. Pelletier, W. George Lai

Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott

Covariates of Amikacin Clearance in Neonates: The Impact of Postnatal Age on Predictability

Journal: Drug Metabolism Letters
Volume: 2 Issue: 4 Year: 2008 Page: 286-289
Author(s): Karel Allegaert, Isabelle Scheers, Veerle Cossey, Brian J. Anderson

Scaling In Vivo Pharmacokinetics from In Vitro Metabolic Stability Data in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 159-169
Author(s): Wendy Klopf, Philip Worboys

The Prediction of the Hepatic Clearance of Tanshinone IIA in Rat Liver Subcellular Fractions: Accuracy Improvement

Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 39-45
Author(s): Guang-Ji Wang, Peng Li, Jing Li, Qian Zhang, Xin Liu, Alexander Khlentzos, Michael S. Roberts

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