Search Result "Leucine rich repeat kinase 2"


Inhibitors of Leucine-Rich Repeat Kinase 2 (LRRK2): Progress and Promise for the Treatment of Parkinson’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 10 Year: 2015 Page: 927-938
Author(s): Paul J. Gilligan

Review Article

Recent Update on the Development of Leucine-Rich Repeat Kinase 2(LRRK2) Inhibitors: A Promising Target for the Treatment of Parkinson’sDisease

Journal: Medicinal Chemistry
Volume: 18 Issue: 7 Year: 2022 Page: 757-771
Author(s):

Leucine-Rich Repeats (LRRs): Structure, Function, Evolution and Interaction with Ligands

Journal: Drug Design Reviews - Online (Discontinued)
Volume: 2 Issue: 4 Year: 2005 Page: 305-322
Author(s): Norio Matsushima, Purevjav Enkhbayar, Masakatsu Kamiya, Mitsuru Osaki, Robert H. Kretsinger

Novel Leucine Rich Repeat Domains in Proteins from Unicellular Eukaryotes and Bacteria

Journal: Protein & Peptide Letters
Volume: 21 Issue: 3 Year: 2014 Page: 292-305
Author(s): Hiroki Miyashita,Yoshio Kuroki,Norio Matsushima

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 5 Year: 2016 Page: 400-414
Author(s): Nora Hermes,Stefanie Kewitz,Martin S. Staege

Kinases as Targets for Parkinsons Disease: From Genetics to Therapy

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 10 Issue: 6 Year: 2011 Page: 724-740
Author(s): Renee Vancraenenbroeck, Evy Lobbestael, Marc De Maeyer, Veerle Baekelandt, Jean-Marc Taymans

Review Article

The Role of LRRK2 in Neurodegeneration of Parkinson Disease

Journal: Current Neuropharmacology
Volume: 16 Issue: 9 Year: 2018 Page: 1348-1357
Author(s): Qin Rui,Haibo Ni,Di Li,Rong Gao,Gang Chen

Research Article

Chemical IN04 Inhibits the Kinase Domain not the ROC Domain of LRRK1: Results from Homology Modeling and Molecular Docking

Journal: Medicinal Chemistry
Volume: 17 Issue: 10 Year: 2021 Page: 1140-1150
Author(s): Zhenhang Chen,Weirong Xing,Li Fan

Review Article

Kinase Inhibitors Involved in the Regulation of Autophagy: MolecularConcepts and Clinical Implications

Journal: Current Medicinal Chemistry
Volume: 30 Issue: 13 Year: 2023 Page: 1502-1528
Author(s): Srinivasa Rao Sirasanagandla,Kondaveeti Suresh Babu,Ramakrishna Gopala Sumesh Sofin

LRRK2 Kinase Inhibition as a Therapeutic Strategy for Parkinson’s Disease, Where Do We Stand?

Journal: Current Neuropharmacology
Volume: 14 Issue: 3 Year: 2016 Page: 214-225
Author(s): Jean-Marc Taymans,Elisa Greggio

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