Search Result "low clearance compounds"
A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds
Journal: Drug Metabolism Letters
Volume: 10 Issue: 1 Year: 2016 Page: 3-15
Author(s): Chi-Chi Peng,Utkarsh Doshi,Chandra Prakash,Albert P. Li
Predicting Clearance in Humans from In Vitro Data
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach
The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles
Journal: Drug Metabolism Letters
Volume: 14 Issue: 2 Year: 2021 Page: 126-136
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao
ARC - Augmented Renal Clearance
Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman
Ion Exchange Chromatography of Proteins and Clearance of Aggregates
Journal: Current Pharmaceutical Biotechnology
Volume: 10 Issue: 4 Year: 2009 Page: 421-426
Author(s): Y. Yigzaw, P. Hinckley, A. Hewig, G. Vedantham
Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance
Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott
Airway Clearance of Apoptotic Cells in COPD
Journal: Current Drug Targets
Volume: 12 Issue: 4 Year: 2011 Page: 460-468
Author(s): Violet R.S. Mukaro, Sandra Hodge
A High Throughput, 384-Well, Semi-Automated, Hepatocyte Intrinsic Clearance Assay for Screening New Molecular Entities in Drug Discovery
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 18 Issue: 5 Year: 2015 Page: 442-452
Author(s): Lance Heinle,Vincent Peterkin,Sonia M. de Morais,Gary J. Jenkins,Ilaria Badagnani
Pharmacokinetics of Drugs in Neonates: Pattern Recognition Beyond Compound Specific Observations
Journal: Current Pharmaceutical Design
Volume: 18 Issue: 21 Year: 2012 Page: 3119-3146
Author(s): Anne Smits,Aida Kulo,Jan N de Hoon,Karel Allegaert
Clearance of Beta-Amyloid in the Brain
Journal: Current Medicinal Chemistry
Volume: 21 Issue: 35 Year: 2014 Page: 4085-4090
Author(s): Masaki Ueno,Yoichi Chiba,Koichi Matsumoto,Toshitaka Nakagawa,Hiroshi Miyanaka