Search Result "Unbound Drug Fraction."
The Role of Unbound Drug in Pharmacokinetics/Pharmacodynamics and in Therapy
Journal: Current Pharmaceutical Design
Volume: 12 Issue: 8 Year: 2006 Page: 977-987
Author(s): Rosario Calvo, John C. Lukas, Monica Rodriguez, Nerea Leal, Elena Suarez
Insight into Tissue Unbound Concentration: Utility in Drug Discovery and Development
Journal: Current Drug Metabolism
Volume: 14 Issue: 3 Year: 2013 Page: 324-340
Author(s): T. Thanga Mariappan,Sandhya Mandlekar,Punit Marathe
Liquid Chromatography-Tandem Mass Spectrometry to Monitor Unbound and Total Ceftriaxone in Serum of Critically Ill Patients
Journal: Current Clinical Pharmacology
Volume: 15 Issue: 0 Year: 2020 Page: 1-10
Author(s): Sjoerd Meenks,Jos le Noble,Norbert Foudraine,Frank de Vries,Paddy Janssen
In Silico Prediction of Brain Exposure: Drug Free Fraction, Unbound Brain to Plasma Concentration Ratio and Equilibrium Half-Life
Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 813-820
Author(s): Morena Spreafico, Matthew P. Jacobson
Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 450-466
Author(s): Xingrong Liu, Cuiping Chen, Cornelis E.C.A. Hop
A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery
Journal: Drug Metabolism Letters
Volume: 13 Issue: 2 Year: 2019 Page: 78-94
Author(s): Liyue Huang,Mary C. Wells,Zhiyang Zhao
CSF as a Surrogate for Assessing CNS Exposure: An Industrial Perspective
Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 46-59
Author(s): Jiunn H. Lin
Fractionation Techniques Improve the Proteomic Analysis of Human Serum
Journal: Current Pharmaceutical Analysis
Volume: 4 Issue: 2 Year: 2008 Page: 69-77
Author(s): Pierluigi Mauri, Andrea Petretto, Davide Cuccabita, Fabrizio Basilico, Dario Di Silvestre, Isabella Levreri, Giovanni Melioli
Molecular Modeling Approaches for the Prediction of Selected Pharmacokinetic Properties
Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 26 Year: 2018 Page: 2230-2238
Author(s): Emilio S. Petito,David J.R. Foster,Michael B. Ward,Matthew J. Sykes
The Impact of In Vitro Binding on In Vitro - In Vivo Extrapolations, Projections of Metabolic Clearance and Clinical Drug-Drug Interactions
Journal: Current Drug Metabolism
Volume: 7 Issue: 3 Year: 2006 Page: 251-264
Author(s): K. Grime, R. J. Riley