Search Result "TDI AUC shift"
Evaluation of Time-Dependent Cytochrome P450 Inhibition in a High-Throughput, Automated Assay: Introducing a Novel Area Under the Curve Shift Approach
Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 43-53
Author(s): Sophie Mukadam, Suzanne Tay, Daniel Tran, Leslie Wang, Erlie M. Delarosa, S. Cyrus Khojasteh, Jason S. Halladay, Jane R. Kenny
Comprehensive Assessment of ADMET Risks in Drug Discovery
Journal: Current Pharmaceutical Design
Volume: 15 Issue: 1 Year: 2009 Page: 2195-2219
Author(s): Jianling Wang
Emerging In Vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions
Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 199-222
Author(s): Cormac Concannon, Desmond A. Hennelly, Simon Noott, Dipak K. Sarker, Chuang Lu, Mingxiang Liao, Lawrence Cohen, Cindy Q. Xia
Assessment of Cytochrome P450 Enzyme Inhibition and Inactivation in Drug Discovery and Development
Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 382-403
Author(s): David O. Nettleton, Heidi J. Einolf
Induction and Inhibition of Drug Metabolizing Enzymes
Ebook: Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates
Volume: 1 Year: 2011
Author(s): Karoly Tihanyi
Doi: 10.2174/978160805120511101010117
Drug Metabolism and Pharmacokinetics in Support of Drug Design
Journal: Current Pharmaceutical Design
Volume: 15 Issue: 1 Year: 2009 Page: 2170-2183
Author(s): Wei Tang, Anthony Y.H. Lu
CYP Inhibition-Mediated Drug-Drug Interactions
Journal: Current Enzyme Inhibition
Volume: 6 Issue: 3 Year: 2010 Page: 130-145
Author(s): Karoly Tihanyi, Monika L. Bakk, Eva Hellinger, Monika Vastag
In Vitro Cytochrome P450 Inhibition and Induction
Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 928-939
Author(s): Robert L. Walsky, Sherri E. Boldt
A Proposed Screening Paradigm for Discovery of Covalent Inhibitor Drugs
Journal: Drug Metabolism Letters
Volume: 8 Issue: 1 Year: 2014 Page: 19-30
Author(s): Mehran F. Moghaddam,Yang Tang,Zhihong OâBrien,Samantha J. Richardson,Maria Bacolod,Prasoon Chaturedi,Julius Apuy,Ashutosh Kulkarni
Nicotinamide Adenine Dinucleotide Based Therapeutics, Update
Journal: Current Medicinal Chemistry
Volume: 22 Issue: 34 Year: 2015 Page: 3991-4028
Author(s): K.W. Pankiewicz,R. Petrelli,R. Singh,K. Felczak