Search Result "β-secretase"


Research Article

Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases

Journal: Current Alzheimer Research
Volume: 15 Issue: 11 Year: 2018 Page: 1045-1052
Author(s): Zhiyou Cai,Chuanling Wang,Wenbo He,Yi Chen

Computer-Aided Drug Design Applied to Beta and Gamma Secretase Inhibitors-Perspectives for New Alzheimer Disease Therapy

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 4 Year: 2006 Page: 311-328
Author(s): Speranta Avram, Adina L. Milac, Dan F. Mihailescu, Aurelia Dabu, Maria L. Flonta

Review of Synthesis, Assay, and Prediction of β and γ-secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 828-844
Author(s): Helena Nino,Jose Enrique Rodriguez-Borges,Xerardo Garcia-Mera,Francisco Prado-Prado

Design of Some New Potent Beta-secretase Inhibitors Based on QSAR and Molecular Modeling Study on a Series of Hydroxyethylamine Derivatives

Journal: Letters in Drug Design & Discovery
Volume: 10 Issue: 3 Year: 2013 Page: 253-265
Author(s): YashShree Pandey,Satya Prakash Gupta

Beta-Secretase: Structure, Function, and Evolution

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7 Issue: 3 Year: 2008 Page: 278-294
Author(s): Chitra Venugopal, Christina M. Demos, K. S. Jagannatha Rao, Miguel A. Pappolla, Kumar Sambamurti

2D QSAR Studies on Series of Human Beta-secretase (BACE-1) Inhibitors

Journal: Medicinal Chemistry
Volume: 10 Issue: 2 Year: 2014 Page: 162-173
Author(s): Daniela Santos Cruz, Marcelo Santos Castilho

Review Article

Current Updates on the Regulation of Beta-Secretase Movement as a Potential Restorative Focus for Management of Alzheimer's Disease

Journal: Protein & Peptide Letters
Volume: 26 Issue: 8 Year: 2019 Page: 579-587
Author(s): Syed Sayeed Ahmad,Mohammad Amjad Kamal

Memapsin 2 (Beta-Secretase) Inhibitors: Drug Development

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 121-131
Author(s): Arun K. Ghosh, Nagaswamy Kumaragurubaran, Ling Hong, Gerald Koelsh, Jordan Tang

Memapsin 2 (Beta-Secretase) Inhibitor Drug, between Fantasy and Reality

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 418-422
Author(s): Arun K. Ghosh, Geoffrey Bilcer, Lin Hong, Gerald Koelsch, Jordan Tang

Research Article

Prediction of Anti-Diabetic Drugs as Dual Inhibitors Against Acetylcholinesterase and Beta-Secretase: A Neuroinformatics Study

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15 Issue: 10 Year: 2016 Page: 1216-1221
Author(s): Sibhghatulla Shaikh,Syed Mohd. Danish Rizvi,Tabinda Suhail,Shazi Shakil,Adel M. Abuzenadah,Rukhsar Anis,Deeba Naaz,Ashraf Dallol,Mohd. Haneef,Adnan Ahmad,Latafat Choudhary

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