This book provides an in-depth and comprehensive overview of andrographolides and their analogues, highlighting their botanical origins, phytochemistry, pharmacological properties, and biotechnological applications. It explores the isolation, purification, and spectroscopic characterization of andrographolides from natural sources, emphasizing their therapeutic potential in antidiabetic studies and other medicinal uses. The book also explains cultivation techniques, agronomic strategies for Andrographis species, genetic improvements, and in vivo extraction methods aimed at enhancing andrographolide yields, with a focus on commercial cultivation and export strategies. Dedicated chapters, contributed by experts, discuss the ethnobotanical significance of Andrographis species, traditional medicinal formulations, and advanced biotechnological interventions for conservation and utilization. Recent breakthroughs in understanding andrographolides'biosynthesis, metabolism, safety aspects, and promising applications in treating diabetes, cancer, inflammation, liver diseases, and neurological disorders are also covered. Readers will gain insight into how andrographolide analogues can be developed as "lead molecules" for creating next-generation phytodrugs. Key Features - Provides a comprehensive account of andrographolide-producing plant sources and their phytochemical and pharmacological properties. - Explores the role of biotechnology in enhancing andrographolide production through in vivo and in vitro methods. - Highlights the therapeutic efficacy of andrographolides and analogues in antidiabetic, anticancer, hepatoprotective, and anti-inflammatory drug development. - Discusses cutting-edge advancements in the biosynthesis and semisynthetic derivatives of andrographolides. - Covers cultivation, agronomic techniques, and genetic improvements to optimize andrographolide production for commercial applications. This book is a valuable resource for researchers, pharmacologists, biotechnologists, and biomedical professionals focused on natural product-based drug discovery involving andrographolide.

Anthocyanins are a diverse group of phytochemicals used for the treatment and management of acute and chronic ailments. This book is a comprehensive guide to anthocyanins and their importance as pharmaceutical and nutraceutical agents. The book provides detailed information about anthocyanin sources and their application in the treatment of diseases including cancer, gastric disorders, infertility, metabolic diseases, and neurological disorders. Key features · Explains the importance of phytochemicals and nutraceuticals · Provides details of anthocyanin sources and mechanisms of action · Includes chapters dedicated to the use of anthocyanins to treat specific diseases · Provides a summary of the market for anthocyanins as a pharmaceutical and nutraceutical product · Includes scientific references

The Roles and Responsibilities of Clinical Pharmacists in Hospital Settings is a comprehensive textbook designed to equip graduate pharmacy students and residents with the essential skills and knowledge needed for effective clinical pharmacy practice in hospitals. This book emphasizes the multidisciplinary nature of clinical pharmacy and the importance of adhering to international guidelines and standards. The book provides an overview of hospital pharmacy practice with an introduction to the essential requirements of a hospital environment, followed by a detailed exploration of clinical pharmacist roles across major medical subspecialties, including internal medicine, infectious diseases, intensive care, pediatrics, cardiology, and oncology. Key Features General and specialized Roles: Comprehensively covers different aspects of clinical pharmacology from basics to medical subspecialties Practical Insights: Offers practical tools, reference resources, and strategies for clinical pharmacy practice across different hospital departments. Advanced Practice: Guides readers from foundational knowledge to advanced clinical pharmacy practices, preparing them for specialized roles within hospital settings. Global Standards: Highlights the importance of multidisciplinary education and adherence to global clinical pharmacy standards. This textbook is an essential resource for pharmacy students, specialist assistants, and anyone pursuing a career in clinical pharmacy.

This book aims to fill research gaps in the search for chemotherapeutic and chemopreventive natural compounds. It includes a collection of detailed reviews focusing on bioactive compounds from plant sources that can be beneficial for cancer therapy. Topics covered include the role of antioxidants in cancer therapy, medicinal plants for cancer chemotherapeutics, bioactive compounds from marine plants, and a review of inhibiting nitric oxide reactions for preventing cancer. Chapters are contributed by researchers who have provided detailed lists and descriptions of the relevant plant sources, the compounds and the biochemical reactions. The book includes references for advanced reading. This book is intended as a reference for scholars and healthcare professionals studying natural medicines for cancer prevention and treatment.

Drug Addiction Mechanisms in the Brain explores the fascinating world of drug substances and their effects on the brain. This book provides a comprehensive overview of the ten major substances that contribute to drug addiction Information about each substance is presented in a specific chapter, shedding light on their biochemical mechanisms and physiological effects. From the stimulating effects of cocaine to the sedative properties of heroin, and the hallucinogenic experiences induced by LSD, the book takes the reader through the intricate pathways of addiction. Other substances covered in the book include alcohol, nicotine, MDMA, METH, morphine, ketamine, and fentanyl. Readers will gain an understanding about neurochemical alterations in the brain Anyone looking for interesting knowledge about the addictive nature of common drugs and their complex interplay with the brain will find this book informative.

Software and Programming Tools in Pharmaceutical Research is a detailed primer on the use for computer programs in the design and development of new drugs. Chapters offer information about different programs and computational techniques in pharmacology. The book will help readers to harness computer technologies in pharmaceutical investigations. Readers will also appreciate the pivotal role that software applications and programming tools play in revolutionizing the pharmaceutical industry. The book includes nine structured chapters, each addressing a critical aspect of pharmaceutical research and software utilization. From an introduction to pharmaceutical informatics and computational chemistry to advanced topics like molecular modeling, data mining, and high-throughput screening, this book covers a wide range of topics. Key Features: - Practical Insights: Presents practical knowledge on how to effectively utilize software tools in pharmaceutical research. - Interdisciplinary Approach: Bridges the gap between pharmaceutical science and computer science - Cutting-Edge Topics: Covers the latest advancements in computational drug development, including data analysis and visualization techniques, drug repurposing, pharmacokinetic modelling and screening. - Recommendations for Tools: Includes informative tables for software tools - Referenced content: Includes scientific references for advanced readers The book is an ideal primer for students and educators in pharmaceutical science and computational biology, providing a comprehensive foundation for this rapidly evolving field. It is also an essential resource for pharmaceutical researchers, scientists, and professionals looking to enhance their understanding of software tools and programming in drug development.

Unlock success in pharmaceutical exams with Objective Pharmaceutics: A Comprehensive Compilation of Questions and Answers for Pharmaceutics Exam Prep. This guide is meticulously crafted to tackle the challenges of pharmaceutics exams through a diverse range of questions. It covers multiple choice questions, concise one-liners, and true/false statements, mirroring the formats commonly found in drug inspector, pharmacist, GPAT, nursing exams, and more. Key Features: Exam-Ready Questions: Prepare for a variety of medical exams with more than 2000 carefully curated questions. Diverse Testing Formats: Master multiple choice, one-liner, and true/false questions for a well-rounded exam readiness. Broad Assessment: Tailored for drug inspectors, pharmacists, GPAT aspirants, and other medical professionals. Build Thinking Capabilities: Progress from simple to challenging questions, enhancing critical thinking skills. This thorough guide empowers you to learn the key topics in pharmaceutics and navigate the most challenging questions in your exam prep journey.

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set serves as a reference guide to pharmacists on aspects of the chemical basis of drug action. Medicinal Chemistry of Drugs Affecting Cardiovascular and Endocrine Systems is the third volume of the series. This volume features 8 chapters focusing on a comprehensive account of drugs affecting both the cardiovascular system and the endocrine functions. The volume informs readers about the medicinal chemistry of relevant drugs, which includes the mechanism of drug action, detailed structure-activity relationships and metabolism. Topics covered include drugs that affect the renin-angiotensin system, calcium channel blockers, diuretics, hematological agents (anticoagulants, thrombolytic and antiplatelet agents), antidiabetics, antihistamines, proton pump inhibitors and therapeutic hormones. Each chapter also offers case studies and self-assessments to facilitate discussion and learning. The book equips students with a scientific foundation to competently evaluate, recommend and counsel patients and health care professionals regarding the safe, appropriate, and cost-effective use of medications. Students and teachers will also be able to integrate the knowledge presented in the book and apply medicinal chemistry concepts to understand the pharmacodynamics and pharmacokinetics of therapeutic agents in the body. The information offered by the book chapters will give readers a strong neuropharmacology knowledge base required for a practicing pharmacist.

Advanced Pharmacy is a textbook dedicated to advanced applications in pharmacy. The book balances information by including chapters that give basic knowledge and inform readers on the latest insights in pharmaceutical science. Authored by pharmacology experts and academics, each chapter highlights current knowledge in the field, presenting research in a didactic and educational manner for academics, researchers, and students who need to understand pharmacy. Additional features of the book include chapter summaries and references for advanced readers. Topics: Physical Pharmacy: Covers foundations of physical pharmacy, providing a solid understanding of the subject. Preformulation Studies: examines active pharmaceutical ingredient-excipent compatibility studies, a crucial aspect of drug formulation. Medicinal Chemistry Applications: explores medicinal chemistry applications using QSAR/QSPR theory. Computer-assisted Study: explains computer-assisted studies with the example of garlic organosulfur as an antioxidant agent. Enzymes in Biocatalysis: sheds light on enzyme characteristics, kinetics, production, and applications in biocatalysis. Antifungal Agents: provides insights into antifungal agents and their significance. Polysaccharides in Drug Delivery: explores the use of naturally and chemically sulfated polysaccharides in drug delivery systems. Immunomodulatory Plant Extracts: covers the evaluation of safety and benefits of immunomodulatory plant extracts. Biofilms and Persistent Cells: examines the development, causes, and consequences of biofilms and persistent cells. Analytical Methods for Drug Analysis: focuses on the development of analytical methods for analyzing drugs of abuse using experimental design. Steric Exclusion Chromatography: discusses steric exclusion chromatography, including chromatography of polymers in aqueous solutions. Intrinsic Viscosity Methods: explores intrinsic viscosity methods in natural polymer pharmaceutical excipients. Extraction Techniques in Green Analytical Chemistry: highlight environment-firendly techniques in analytical chemistry. Advanced Pharmacy is a comprehensive resource that bridges the gap between pharmaceutical research and practice, offering invaluable insights into the latest developments in the field. This textbook serves as an essential reference for both learners and scholars in basic and advanced courses in pharmacy and pharmaceutical science.

Plant-derived Hepatoprotective Drugs is a comprehensive guide that explores the world of medicinal plants and their hepatoprotective properties, offering both basic and applied insights for scholars and hepatology residents. Structured chapters provide a deep dive into the subject, while referencing relevant research and future perspectives. Readers will learn the science behind hepatotoxicity and the role of plants in safeguarding liver health. The book also helps researchers to explore bioactive compounds extracted from plants, along with herbal formulations that contribute to hepatoprotection, and conveys an understanding of the effects of edible plants and spices on liver wellness. A chapter focusing on isolation and characterization of phytochemicals bridges theory and application for discovering and developing hepatoprotective biopharmaceuticals. Key Features: Gives a thorough understanding of hepatotoxicity and related bioactive compounds Comprehensive references to enhance understanding Well-structured chapters providing organized knowledge Basic and applied information for diverse readers Future perspectives offering a glimpse into ongoing research This is an ideal reference for pharmacology scholars and residents in hepatology, as well as readers interested in nature's potential in promoting liver health.