Advances in technology have enabled medicinal chemists to discover and formulate several highly specific, biocompatible, and non-toxic therapeutic agents for clinical applications. Nanotechnology has achieved significant progress in the last few decades and is crucial in every field of science and technology. Nanotechnology-based pharmaceuticals offer multifaceted and alternative methodologies in comparison to the limitations of many conventional clinical therapies. Expertise in designing and developing nanoformulations has helped in targeted drug delivery. Recently, the use of innovative therapeutic agents, particularly in nanomedicine, has accounted for a significant portion of the global pharmaceutical market and is predicted to continue to grow rapidly in the near future. Nanotherapeutic Strategies and New Pharmaceuticals is an accessible multi-part reference which informs the reader about several new techniques based on nanotechnology. The chapters explain relevant topics in detail. The book is designed to encourage and help undergraduate, graduate and post-graduate students in the field of nanotherapeutics, pharmaceuticals and bio-organic chemistry through the use of didactic language and simple illustrations. Part 2 of this book covers the potential of nanotherapeutics and natural therapies for treating neurological diseases, targeting ion channels, signal transduction therapy, gene therapy of single gene mutation diseases and for nanoformulations for special purposes such as wound healing and stimuli-responsive drug delivery. The book also features a chapter that summarizes the types of nanoparticles tailored for specific molecular targets that mediate different diseases. The book set serves as a textbook for students in pharmacology and medical biochemistry, as well as a quick reference for researchers on bio-organic chemistry, as well as general readers interested in nanomedicine.

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. Volume eight of the series brings seven reviews covering these main themes: marine natural products, neuroprotective natural products, chromenes, coumarin derivatives, and psychedelics. The chapters featured in this volume are: - Chemistry, Antiviral Properties and Clinical Relevance of Marine Macroalgae and Seagrass - Quinolizidine Alkaloids from Marine Organisms: A Perspective On Chemical, Bioactivity and Synthesis - Towards The Use of Whole Natural Products in Psychedelic Research and Therapy: Synergy, Multi-Target Profiles, and Beyond - Neuroprotective Effects of Polyphenols - Neuroprotection with the Functional Herbs from the Lamiaceae Family - Coumarin Derivatives as Potential Anti-Inflammatory Agents for Drug Development - Recent Progress in The Synthesis and Biological Activity of Chromene and Its Derivatives

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. <p> Volume seven of the series brings seven reviews covering these topics: <p> - Plant-Derived Anticancer Compounds Used in Cancer Therapies <p> - Pradimicin and Benanomicin Antibiotics <p> - The Chemical Compositions of Bixa orellana and their Pharmacological Activities <p> - Overview of Phytochemistry and Pharmacology of Nilakanthi (Ajuga bracteosa Wall. ex Benth.) <p> - Tetracyclic benzocarbazoles and derivatives <p> - Chalcones as Antiinflammatory, Antidiabetic, and Antidepressant Agents <p> - Bioactive Steroids from Marine Organisms

Advances in technology have enabled medicinal chemists to discover and formulate several highly specific, biocompatible, and non-toxic therapeutic agents for clinical applications. Nanotechnology has achieved significant progress in the last few decades and is crucial in every field of science and technology. Nanotechnology-based pharmaceuticals offer multifaceted and alternative methodologies in comparison to the limitations of many conventional clinical therapies. Expertise in designing and developing nanoformulations has helped in targeted drug delivery. Recently, the use of innovative therapeutic agents, particularly in nanomedicine, has accounted for a significant portion of the global pharmaceutical market and is predicted to continue to grow rapidly in the near future. Nanotherapeutic Strategies and New Pharmaceuticals is an accessible multi-part reference which informs the reader about several new techniques based on nanotechnology. The chapters explain relevant topics in detail. The book is designed to encourage and help undergraduate, graduate and post-graduate students in the field of nanotherapeutics, pharmaceuticals and bio-organic chemistry through the use of didactic language and simple illustrations. Part 1 of this book set explains general advances in nanomedicine, followed by chapters covering the role of nanotherapeutics in hematology and cancer treatment, as well as specific types of nanomaterials based on different components (such as boron, graphene, silver and other metals). The book also features a chapter that summarizes the processes for designing nanoparticles tailored for specific targets. The book serves as a textbook for students in pharmacology and medical biochemistry, as well as a quick reference for researchers on bio-organic chemistry, as well as general readers interested in nanomedicine.

This reference presents comprehensive information about laser surface treatments for tribological applications. Chapters of the book highlight the importance of laser technology in modifying materials to optimize the effects of friction and lubrication, by explaining a range of surface modification methods used in industries. These methods include hardening, melting, alloying, cladding and texturing. The knowledge in the book is intended to give an in-depth understanding about the role of laser technology in tribology and the manufacture of industrial materials and surfaces for special applications. Key Features: - 10 chapters on topics relevant to tribology and industrial applications of laser material processing - Comprehensively covers laser surface modification of metals and alloys - Explains a wide range of surface modification methods (hardening, melting, alloying, cladding and texturing) - Covers material and tribological characterization of surfaces - Presents information in a simple structured layout for easy reading, with introductory notes for learners - Provides references for further reading This book is an ideal reference for students and learners in courses related to engineering, manufacturing and materials science. Researchers, industrial professionals and general readers interested in laser assisted machining processes and surface modification techniques will also find the book to be an informative reference on the subject.

Chemical Modification of Solid Surfaces by the Use of Additives brings ten comprehensive chapters covering different types of solid surface modifications by using surfactants or other chemicals. Each chapter explains different types of chemical surface modifications that are important for a large variety of applications. The uses of each type of modification is summarized to give the reader an overview of recent developments in this field of materials science. The book also highlights the importance of surface modification for the biomedical application of polysaccharides, sensing application of carbon electrode, metal coating substrate surfaces, microelectronic, microwave applications of perovskite material and the role of nanotechnology. This book is a useful reference for chemical engineering and civil engineering students who wish to understand the surface chemistry of additive materials. Scholars undertaking courses in nanotechnology and environmental science will also benefit from the information presented by the book.

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. Contents of this volume include: - Metal-Free and Acid-Free Activation of Carbonyl Moiety Using Molecular Halogens or N-Halamines - Anti-algal Study on Polymeric Coating Containing Metal-Metal Oxide Core-shell Nanoparticles - Functionalized Catalyst for Efficient Nucleophilic and Electrophilic Fluorination - Synthesis and Applications of Small Fluorescent Molecules - Recent Achievements in the Synthesis of Aromatic Five-Membered Heterocycles Containing One Heteroatom - Basic Ionic Liquid Catalyzed Cycloaddition Reactions for the Synthesis of 1, 2, 3-Triazoles

Medicinal and Environmental Chemistry: Experimental Advances and Simulations is a collection of topics that highlight the use of pharmaceutical chemistry to assess the environment or make drug design and chemical testing more environment friendly. The eleven chapters included in the second part of this book set cover diverse topics, blending the fields of environmental chemistry and medicinal chemistry and have been authored by experts, scientists and academicians from renowned institutions. This part is more specialized in nature, focusing primarily on the effects of air pollution and water contamination on human health. Chapters covering pharmaceutical interventions and pollution control measures, respectively follow these initial topics. Part II also features specialized topics that aim to address some unique challenges of the above mentioned problems including antibiotic pollution, pharmaceutical analysis of pollutants, chemosensors, biosteric modifications and new drug development strategies against SARS-CoV2. Key Features: 1. 11 topics which blend environmental chemistry and medicinal chemistry 2. Contributions from more than 40 experts 3. Includes topics covering effects of air pollution on human health and disease 4. Includes specialized topics on pharmaceutical analysis in the environment, and modifications of compounds for pharmaceutical purposes 5. Bibliographic references This reference is an essential source of information for readers and scholars involved in environmental chemistry, pollution management and pharmaceutical chemistry courses at graduate and undergraduate levels. Professionals and students involved in occupational medicine will also benefit from the wide range of topics covered.

Medicinal and Environmental Chemistry: Experimental Advances and Simulations is a collection of topics that highlight the use of pharmaceutical chemistry to assess the environment or make drug design and chemical testing more environment friendly. The ten chapters included in the first part of this book set cover diverse topics, blending the fields of environmental chemistry and medicinal chemistry and have been authored by experts, scientists and academicians from renowned institutions. The book introduces the reader to environmental contaminants and techniques for their quantification and removal. A medicinal perspective for effects and remediation of environmental hazards, and therapeutic strategies available to design new and safer drugs, is addressed with a focus on knowledge about experimental and simulation methods. To further elaborate the importance of environmentally safe chemical practice, the concept of green chemistry has also been covered. Specialized chapters have been included in the book about persistent organic pollutants, heavy metal and plastic pollutants, the effect of environmental xenoesterogens on human health and the potential of natural products to combat ecotoxicity. Key Features: 1. 10 topics which blend environmental chemistry and medicinal chemistry 2. Contributions from more than 30 experts 3. Includes introductory topics on environmental pollutants, investigative techniques in drug design and environmental risk assessment and green chemistry 4. Includes specialized topics on persistent pollutants, ecotoxicity remediation and xenoestrogens 5. Bibliographic references This reference is an essential source of information for readers and scholars involved in environmental chemistry, pollution management and pharmaceutical chemistry courses at graduate and undergraduate levels. Professionals and students involved in occupational medicine will also benefit from the wide range of topics covered.

This book is a guide for researchers, academics and experimentalists who wish to explore density functional theory (DFT) on selected molecular systems. The salient features of the book include concise and complete coverage of DFT on biologically active molecules, a basic guide to DFT for beginners followed by its computational application using a powerful Gaussian program. Subsequently, discussions on synthetic compounds, amino acids, and natural products have been offered by the authors for the benefit of the reader. The book also features an exclusive chapter on the quantum theory of atoms in molecules and is supplemented by an appendix on the Gaussian output for methane. Key Features: &middot; basic introduction of density functional theory &middot; practical introduction to Gaussian program &middot; interpretation of input and output files &middot; explanation of calculated parameters &middot; examples of several bioactive molecules (syenthetic and natural) &middot; correlation between theory and experiments &middot; exploration of the hydrogen bonds &middot; appendix covering Gaussian outputs for methane &middot; beginner friendly text &middot; references at the end of each chapter DFT Based Studies on Bioactive Molecules is a suitable handbook for academics, students and researchers who are learning the basic biophysics and computational chemistry of bioactive molecules with reference to DFT models.