The interactions between carbohydrates and proteins have been extensively explored in a wide range of physiological and pathological processes over several decades. The recent emergence of glycomics has strengthened this interest and notably contributed to spectacular progress in understanding how carbohydrates mediate and regulate complex biological events. Synthesis and Biological Applications of Glycoconjugates gives a summary of contemporary findings in glycoconjugate research. Readers will be updated on major achievements in chemical methods and biological applications employed in modern glycomics. The Ebook should be of interest to a broad community of students and professional researchers in both academia and industry.

Sustainable Utilization of Fungi in Agriculture and Industry covers current knowledge about of different fungal microorganisms, including economically important filamentous fungi and yeasts. 22 chapters summarize recent information about scientific investigations and the application of fungi in the production of industrial enzymes, organic acids (citric acid, lactic acid, etc.), biofuel (ethanol, H2 gas) and bioactive compounds for sustainable processes in agriculture, bioremediation, industries and therapeutics. Each chapter gives an updated and detailed account of knowledge on fungal microbes and their sustainable utilization in agriculture, white biotechnology, and other valuable industrial applications. Contributions are made by academic and professional experts in mycology and industrial biotechnology, presenting a broad perspective of the field in a simple, yet engaging style. Sustainable Utilization of Fungi in Agriculture and Industry is an informative reference for general readers, trainees, interested in sustainability measures in agriculture and industry. It also serves as reading materials for scholars, students and teachers involved in botany, microbiology, biotechnology and life sciences courses.

When environmental conditions deviate from the optimal range, stress ensues. Stress response is a set of reactions that allow the organism to adjust and survive adverse conditions. Stress can be physical, such as extreme temperature, radiation, injury, or psychological, caused by perceived danger or deprivation. Every living cell has biochemical mechanisms to cope with physical stress. These mechanisms show a degree of similarity among several types of living organisms. <p></p> Stress Response and Immunity: Links and Trade Offs explores the functional and evolutionary connections between stress response and immunity. The book introduces the reader to the concept of stress and subsequently examines the connection between stress response and immunity at various evolutionary stages of living organisms - from bacteria to humans. The book also features chapters dedicated to the role of tumor suppressor genes and the immune system of the brain. <p></p> The information presented in this reference demonstrates the profound effects of physical and psychological stress on human health. Readers with basic knowledge of molecular biology will learn about the interesting facets of stress responses and the evolutionary trade offs observed in different life forms.

Sperm-mediated gene transfer (SMGT) represents a novel set of technologies for animal (or in the future, human) genetic modification using the sperm as a vector, as opposed to more traditional established routes such as fertilized eggs or embryonic stem cells. Studies of sperm-mediated gene transfer (SMGT) indicate that sperm cells possess the ability to be utilized as carriers of exogenous genetic sequences, offering the potential of a novel cost-effective route for germline genetic modification. The fate of transgenes borne by sperm cells has been inconsistent, and analysis of offspring from SMGT experiments has shown a mixed picture in terms of genomic integration of the transgene, suggesting an episomal mode of inheritance. Various distinct steps in transgene uptake by the sperm cell have been described or proposed, including a model based upon endogenous reverse transcriptase activity. Although mature sperm cells are naturally protected against uptake of foreign nucleic acid molecules, certain environmental conditions, for example at key times within the reproductive tract, may reduce this protection, suggesting that SMGT may occasionally take place in nature. If correct, this carries profound implications for evolution and human genetic health. This e-book brings together theoretical and empirical reviews from experts in SMGT, providing comprehensive coverage of the major trends, developments and controversies in this novel field. This e-book is intended as a reference for professional researchers in the field of animal genetic modification (transgenesis) as well as teachers, scientists and physicians interested in medical genetics in general and gene therapy in particular.

Spatial Ecology elucidates processes and mechanisms which structure dynamics of real world systems; these include lakes, ponds, forests and rivers. Readers are introduced to contemporary models in ecological literature based on the author’s research experience. The e-book starts by presenting an introduction to basic mechanisms of ecological processes. This is followed by chapters explaining these processes responsible for generating observed spatial patterns in detail. The e-book concludes with a chapter on water quality management and its relevance to the spatial setting in a wetland area. This text in spatial ecology is a welcome resource for readers interested in models, methods and methodologies best suited for the study of advanced ecology courses and topics related to ecosystem structure, function and habitat fragmentation.

Biodiversity and Livelihood: Lessons from Community Research in India Is a compilation of research articles on the ecological biodiversity and local conservation efforts of selected regions in India, and among local communities throughout the county. 18 chapters have been contributed by experts in ecology, sustainability and ethnic studies in India. The chapters provide information on a wide range of tops which cover local communities, their agricultural practices and the ecological relationships between their community and the species on which their livelihood depends. Contributions emphasize different aspects of these topics, such as observational ecological information about the aforementioned regions and communities, the local biodiversity, tribal customs of ethnic communities that are linked to conservation, specific programs which are aimed at the conservation of specific plant and animal species endemic to the region, the benefits shared by the communities involved with conservation programs and recommendations shared by the authors for sustainable management of the regional ecosystem and its resources. Readers will find a wealth of information about biodiversity conservation in different regions in India (most notably the western and eastern ghats and provinces such as Kerala and Andhra Pradesh), from a basic and applied perspective. The book is, therefore, an informative reference for conservationists, ecologists, environmentalists and ethnologists who are studying the biodiversity and conservation of India. Readers involved in sustainable development programs in the region will also find the content valuable to their knowledge.

Bioencapsulation (or microencapsulation) of cells and their implantation into a body of immunoprotected cells allows researchers to revive a missing or defective function in the cells. Microencapsulated cells have reached the clinic where they have been shown to be safe and efficacious in numerous clinical trials. Cell types that have been encapsulated for therapeutic purposes include hybridomas, islet cells, "platform" cell lines e.g. HEK293 and CHO cells as well as an increasing focus on the encapsulation of stem cells. This e-book explains the different methods used for achieving cell bioencapsulation based on different polymers e.g. alginate, cellulose sulphate and agarose. Other chapters in this book subsequently describe the use of cell encapsulation in cancer therapy to improve on existing chemotherapies by reducing doses and thus side effects while increasing efficacy for long term in vivo production of (i) tumoricidal or virus neutralising antibodies, (ii) insulin to achieve a self regulating treatment for diabetes and (iii) neuron nurturing factors to treat CNS diseases such as epilepsy, disorders like Parkinson's disease, Alzheimer, Amyotrophic lateral sclerosis, Huntington's disease and pathologies caused by trauma and/or ischemic processes. The book also includes a chapter reviewing the genetic engineering of cells to allow controlled production of biotherapeutics from encapsulated cells. This is a unique and timely book which brings together contributions from some of the leading researchers in the field of cell encapsulation. Interested readers are provided an overview of the exciting developments and clinical experiences of researchers with cell bioencapsulation.

Individuals with Angelman Syndrome (AS) present many unique challenges to professionals, parents and others who are committed to maximizing individuals’ competence while ensuring them the best possible quality of life. Angelman Syndrome: Communication, Educational, and Related Considerations is a unique, exhaustive compilation of existing material related to understanding the nature of AS and how individuals’ communication and related skills can be fostered most effectively. It provides readers with a comprehensive understanding of the background of Angelman Syndrome along with an in-depth exploration of communication (with a focus on augmentative and alternative communication), educational, and related issues that should be addressed when attempting to meet the needs of individuals with AS at home, school, work, and elsewhere in the community. Key features of the book include: • Extensive background information about medical and related factors behind AS and how they influence individuals’ learning • A series of prologues written by the parents of individuals with AS • Contributions from internationally recognized experts on AS, communication disorders, psychology and education • Numerous practical, evidence-based strategies for conducting assessments and carrying out interventions among AS affected individuals Speech-language pathologists, allied healthcare providers and educators providing support to affected individuals should benefit from the information provided in the book by being able to identify appropriate communication, behavioral and educational goals. Laypersons, particularly parents, will also find the information highly useful in advocating for best practices for their children (which is partly fostered by the series of parental prologues). Angelman Syndrome: Communication, Educational, and Related Considerations will not only serve as a valuable reference for improving the learning experience for AS affected individuals but will also embolden both professionals and parents to maintain higher expectations for them.

This handbook focuses on the use of antibiotic alternatives in poultry and fish feed. Chapters in the book cover a range of natural ingredients in feed and the impacts of these natural feed additives on growth, production, reproduction and health status of poultry and fish. All chapters give a holistic approach to how organic feed additives (herbal plants and their extracts, probiotics, peptides, etc.) can positively impact animal health and production. Key Features: - presents 13 chapters contributed by 38 experts and scientists of animal, poultry and fish nutrition, poultry and fish physiology, toxicology, pharmacology, and pathology - highlights the significance of herbal plants and their extracts and derivatives, cold-pressed and essential oils and fruits by-products - covers the effects of special ingredients such as immunomodulators, antimicrobial peptides, and probiotics - provides the reader an updated perspective on the use of additives in poultry and fish industry as growth promoters and their role in developing bacterial resistance to antibiotics - covers the main poultry species, egg-laying hens, quails, geese, ducks, turkey, and commercial fish - includes references for advanced readers This book will be useful for poultry and fish keepers and researchers in animal nutrition, pharmacology, and veterinary sciences. Professionals involved in the poultry and fish feed industry will also find the information useful for product development.