Therapeutic options for late-stage liver cancer are very limited and the prognosis is often poor. A better understanding of the molecular mechanisms involved in the initiation, progression, and metastasis of hepatocellular carcinoma is critical for developing more rational diagnostic and therapeutic approaches. This e-book covers current developments on clinically relevant research on the molecular biology of hepatocellular carcinoma. It should be a valuable reference for professional gastroenterologists, hepatologists and oncologists as well as medical students and researchers.

Cancer is one of the major causes of death worldwide. Despite hundreds of clinical trials currently in progress for cancer patients, the success rate is still very low. Understanding the molecular aspects of cancer development, the discovery of new molecular targets and rational drug design on this molecular basis should help in discovering early cancer biomarkers as well as novel therapeutic drugs. This book describes various cancer topics on a molecular level and integrates information on the relationship between causes of cancer, cancer cell biology, metastasis, cancer prevention and drug design. This book should prove to be an extraordinary reference text for students, physicians and oncologists.

Multiple drug resistance among bacteria has become a global issue with a considerable impact on the mortality associated with infectious diseases. This book is a detailed compilation of available knowledge on the surveillance and mechanisms of antibiotic resistance in various countries throughout the world. Readers will be updated on current information on the understanding of mechanisms involved in drug resistance and the geographical distribution of resistance determinant markers. This volume should be a useful guide for microbiologists and clinicians interested in designing antimicrobial therapies tailored for patients in specific geographical regions.