Abstract

Ultrasonic irradiation is employed to accelerate organic reactions. Under sonication reduced time, good selectivity, excellent yield, and milder conditions were observed for many organic reactions. Ultrasonic reactions are increasingly used as green, clean, and environment-friendly methods in organic synthesis in terms of energy conservation and waste minimization. The use of ultrasound irradiation is increasing in coming years. The use of ultrasound irradiation in the synthesis of five-membered N-heterocycles is depicted in the present review article.

Keywords: Heterocycles, nitrogen, ultrasound, ultrasonic irradiation, nitrogen heteroatom, pyrrole ring.

Graphical Abstract