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Recent Patents on Nanotechnology

Author(s): Dan Tian, Dan-Ni Yu, Yi-Ming Xu, Xu-Yin Ding, Zhou-Yu Zhang, Chun-Lan Wan and Ji-Huan He*

DOI: 10.2174/1872210513666190426145024

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Electrospun Mussel-derived Silk Fibers

Page: [14 - 20] Pages: 7

  • * (Excluding Mailing and Handling)

Abstract

Background: Though there are many patents on silk, patents on sea silk are rare. Sea silk is one of the most coveted materials in the world, and the technology to make sea silk is at an extremely high risk of extinction. Unlike spider dragline silk and silkworm silk, this natural silk has been forgotten in the academic commune for millennia, though it has many fascinating properties: high strength, remarkable adhesion, extreme lightweight, and others.

Methods: Here we report that mussel-derived silk fibers can be fabricated by electrospinning. Instead of extracting proteins from byssus, we directly use the protein solution from alive blue mussels, which are intensely commercially used. The protein solution and the polyvinyl alcohol solution are mixed together to produce mussel-based silk fibers.

Results: The mussel-based silk fibers have many special properties like high mechanical strength, remarkable super-contraction and good wetting properties.

Conclusion: The electrospinning mussel-based silk fibers have the potential for use as a replacement for the rarest sea silk and as a new bio-inspired material with multi-functions.

Keywords: Electrospinning, nanofiber, natural silk, mussel-based silk fiber, mechanical property, Sea silk, Mytilus edulis, supercontraction.

Graphical Abstract

[1]
Altman GH, Diaz F, Jakuba C, et al. Silk-based biomaterials. Biomaterials 2003; 24(3): 401-16.
[http://dx.doi.org/10.1016/S0142-9612(02)00353-8] [PMID: 12423595]
[2]
Sadia "Ross" Barrameda Methods of producing new types of hybrid silk and hemp fibers US Patent 20150101541A1. 2015.
[3]
Omenetto FG, Kaplan DL. New opportunities for an ancient material. Science 2010; 329(5991): 528-31.
[http://dx.doi.org/10.1126/science.1188936] [PMID: 20671180]
[4]
Shao Z, Vollrath F. Surprising strength of silkworm silk. Nature 2002; 418(6899): 741-1.
[http://dx.doi.org/10.1038/418741a] [PMID: 12181556]
[5]
Smith BL, Schaffer TE, Viani M, et al. Molecular mechanistic origin of the toughness of natural adhesives, fibres and composites. Nature 1999; 399: 761-3.
[http://dx.doi.org/10.1038/21607]
[6]
Jin HJ, Kaplan DL. Mechanism of silk processing in insects and spiders. Nature 2003; 424(6952): 1057-61.
[http://dx.doi.org/10.1038/nature01809] [PMID: 12944968]
[7]
Vollrath F, Knight DP. Liquid crystalline spinning of spider silk. Nature 2001; 410(6828): 541-8.
[http://dx.doi.org/10.1038/35069000] [PMID: 11279484]
[8]
Islam S, Karatzas C, Rodenhiser A. Methods and apparatus for spinning spider silk protein US Patent 20040102614A1. 2004.
[9]
Maeder F, Halbeisen M. Sea-silk: On the trail of a forgotton textile material (Costume material, byssus). Waffen und Kostumkunde 2001; 43: 33-41.
[10]
Yang YJ, Choi YS, Jung D, et al. Production of a novel silk-like protein from sea anemone and fabrication of wet-spun and electrospun marine-derived silk fibers. NPG Asia Mater 2013; 5 e50
[http://dx.doi.org/10.1038/am.2013.19]
[11]
Lee H, Scherer NF, Messersmith PB. Single-molecule mechanics of mussel adhesion. Proc Natl Acad Sci USA 2006; 103(35): 12999-3003.
[http://dx.doi.org/10.1073/pnas.0605552103] [PMID: 16920796]
[12]
Lee BP, Messersmith PB, Israelachvili JN, Waite JH. Mussel-inspired adhesives and coatings. Annu Rev Mater Res 2011; 41: 99-132.
[http://dx.doi.org/10.1146/annurev-matsci-062910-100429] [PMID: 22058660]
[13]
Xia Q, Guo Y, Zhang Z, et al. Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx). Science 2009; 326(5951): 433-6.
[http://dx.doi.org/10.1126/science.1176620] [PMID: 19713493]
[14]
Xia Q, Zhou Z, Lu C, et al. A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science 2004; 306(5703): 1937-40.
[http://dx.doi.org/10.1126/science.1102210] [PMID: 15591204]
[15]
Asakura T. Method of producing fiber and film of silk and silk-like material. US Patent 20030183978A1. 2003.
[16]
Asakura T. Non-woven fabric comprising ultra-fine fiber of silk fibroin and/or silk-like material, and method for production thereof US Patent 20040185737A1. 2004.
[17]
Zhang F, Zuo BQ. High performance natural silk fiber and preparation method thereof EP Patent 3369859A4. 2018.
[18]
Kiyokawa I, Arimatsu Y, Miura T, et al. Chimeric spider silk and uses thereof US Patent 20130212717A1. 2013.
[19]
Malcolm JF, Randy L, Don J, et al. Transgenic silkworms capable of producing chimeric spider silk polypeptides and fibers US Patent 20150322121A1. 2015.
[20]
Stein E, Vigo C. The last woman who makes sea silk - BBC News 6 September 2017.
[21]
Sardinia MP. Chiara Vigo: The last woman who makes sea silk, BBC.. http://www.bbc.com/news/magazine-33691781 [Accessed 2 September 2015]
[22]
Stein E. The last surviving sea silk seamstress BBC Travel 6 September 2017 [Accessed 6 September 2015]
[23]
Sumitra CV. The World’s Last “Sea Silk” Seamstress Oddity Central [Accessed 11 September 2015]
[24]
van Huygen M. Untangling the Secrets of Sea Silk, the Ancient Mediterranean’s Elusive Luxury Textile Mental Floss [Accessed on 2 October 2015]
[25]
Garcia-March JR, Garcia-Carrascosa AM, Cantero ALP, et al. Population structure, mortality and growth of Pinna nobilis Linnaeus, 1758 (Mollusca, Bivalvia) at different depths in Moraira bay (Alicante, Western Mediterranean). Mar Biol 2007; 150: 861-71.
[http://dx.doi.org/10.1007/s00227-006-0386-1]
[26]
Garcia-March Pinna nobilis shells JR, Garcia-Carrascosa AM, Pena AL.. In situ measurement of for age and growth studies: A new device. Marine Ecology-Pubblicazioni dellas Stazione Zoologica di Napoli I 2002; 23: 207-17.
[http://dx.doi.org/10.1046/j.1439-0485.2002.02781.x]
[27]
Li S, Liu C, Zhan A, Xie L, Zhang R. Influencing Mechanism of Ocean Acidification on Byssus Performance in the Pearl Oyster Pinctada fucata. Environ Sci Technol 2017; 51(13): 7696-706.
[http://dx.doi.org/10.1021/acs.est.7b02132] [PMID: 28605591]
[28]
Ye Y, Wu C, Guo B, et al. Isolation and characterization of ten polymorphic microsatellite markers for the blue mussel (Mytilus edulis). Biochem Syst Ecol 2014; 54: 5-7.
[http://dx.doi.org/10.1016/j.bse.2013.12.015]
[29]
Yu DN, Tian D, He JH. Snail-based nanofibers. Mater Lett 2018; 220: 5-7.
[http://dx.doi.org/10.1016/j.matlet.2018.02.076]
[30]
Liu Y-Q, Zhao L, He J-H. Nanoscale multi-phase flow and its application to control nanofiber diameter. Therm Sci 2018; 22(1A): 43-6.
[http://dx.doi.org/10.2298/TSCI160826148L]
[31]
Zhao L, Liu P, He JH. Sudden solvent evaporation in bubble electrospinning for fabrication of unsmooth nanofibers. Therm Sci 2017; 21: 1827-32.
[http://dx.doi.org/10.2298/TSCI160725075Z]
[32]
He JH, Kong HY, Yang RR, et al. Review on fiber morphology obtained by bubble electrospinning and blown bubble spinning. Therm Sci 2012; 16: 1263-79.
[http://dx.doi.org/10.2298/TSCI1205263H]
[33]
He CH, Li XW, Liu P, et al. Bubbfil spinning for fabrication of PVA nanofibers. Therm Sci 2015; 19(2): 743-6.
[http://dx.doi.org/10.2298/TSCI150413061H]
[34]
Tian D, Zhou CJ, He JH. Strength of bubble walls and the Hall-Petch effect in bubble-spinning. Text Res J 2018; 89(7) 004051751877067
[http://dx.doi.org/10.1177/0040517518770679]
[35]
Peng NB, Liu YQ, Xu L, et al. A Rachford-Rice like equation for solvent evaporation in the bubble electrospinning. Therm Sci 2018; 22(4): 1679-83.
[http://dx.doi.org/10.2298/TSCI1804679P]
[36]
Ren ZF, Kong FZ, Wang FY, et al. Effect of bubble size on nanofiber electrospinning. Therm Sci 2016; 20: 845-8.
[http://dx.doi.org/10.2298/TSCI1603845R]
[37]
Work RW. A Comparative study of the supercontraction of major ampullate silk fibers of orb-web-building spiders (Araneae). J Arachnol 1981; 9: 299-308.
[38]
Tian D, Li XX, He JH. Self-assembly of macromolecules in a long and narrow tube. Therm Sci 2018; 22(4): 1659-64.
[http://dx.doi.org/10.2298/TSCI1804659T]
[39]
Tian D, He CH, He JH. Macromolecule orientation in nanofibers. Nanomaterials (Basel) 2018; 8(11): 918.
[http://dx.doi.org/10.3390/nano8110918] [PMID: 30405041]
[40]
Tian D, He JH. Macromolecular electrospinning: Basic concept & preliminary experiment. Res Phy 2018; 11: 740-2.
[http://dx.doi.org/10.1016/j.rinp.2018.10.042]
[41]
Li XX, He JH. Nanoscale adhesion and attachment oscillation under the geometric potential Part 1: The formation mechanism of nanofiber membrane in the electrospinning. Res Phy 2019; 12: 1405-10.
[http://dx.doi.org/10.1016/j.rinp.2019.01.043]
[42]
He CH, Shen Y, Ji FY, et al. Taylor series solution for fractal Bratu-type equation arising in electrospinning process. Fractals 2019.
[http://dx.doi.org/10.1142/S0218348X20500115]