Steroids and Postoperative Complications in IBD

Page: [1323 - 1326] Pages: 4

  • * (Excluding Mailing and Handling)

Abstract

Corticosteroids are frequently used in the management of Inflammatory Bowel Disease. Although they can be very useful, their potential adverse effects have to be kept in mind. One of the situations in which these drugs should be avoided, if possible, is the perioperative setting. If a patient reaches surgery while on steroids, surgical complications will be more likely to occur, both infectious and non-infectious. Attention should be paid to this fact, within a multidisciplinary approach, that also takes into account other factors, such as nutrition.

Keywords: Corticosteroids, surgery, crohn’s disease, ulcerative colitis, complications, inflammatory bowel disease.

[1]
Irving PM, Gearry RB, Sparrow MP, Gibson PR. Review article: appropriate use of corticosteroids in Crohn’s disease. Aliment Pharmacol Ther 2007; 26(3): 313-29.
[2]
Lichtenstein GR1, Feagan BG, Cohen RD, et al. Serious infections and mortality in association with therapies for Crohn’s disease: TREAT registry. Clin Gastroenterol Hepatol 2006; 4: 621-30.
[3]
Stuck AE, Minder CE, Frey FJ. Risk of infectious complications in patients taking glucocorticosteroids. Rev Infect Dis 1989; 11: 954-63.
[4]
Wang AS1, Armstrong EJ, Armstrong AW. Corticosteroids and wound healing: clinical considerations in the perioperative period. Am J Surg 2013; 206: 410-7.
[http://dx.doi.org/10.1016/j.amjsurg.2012.11.018]
[5]
Eriksen TF1. Lassen CB, Gögenur I. Treatment with corticosteroids and the risk of anastomotic leakage following lower gastrointestinal surgery: a literature survey. Colorectal Dis 2014; 16: O154-60.
[http://dx.doi.org/10.1111/codi.12490]
[6]
Agrawal A1, Durrani S, Leiper K, et al. Effect of systemic corticosteroid therapy on risk for intra-abdominal or pelvic abscess in non-operated Crohn’s disease. Clin Gastroenterol Hepatol 2005; 3(12): 1215-20.
[7]
Kumar A, Auron M, Aneja A, Mohr F, Jain A, Shen B. Inflammatory bowel disease: perioperative pharmacological considerations. Mayo Clin Proc 2011; 86: 748-57.
[http://dx.doi.org/10.4065/mcp.2011.0074]
[8]
Gionchetti P, Dignass A, Danese S, et al. Third European evidence-based consensus on the diagnosis and management of crohn’s disease 2016: part 2: surgical management and special situations. J Crohn’s Colitis 2017; 11: 135-49.
[http://dx.doi.org/10.1093/ecco-jcc/jjw169]
[9]
Bruewer M, Utech M, Rijcken EJ, et al. Preoperative steroid administration: effect on morbidity among patients undergoing intestinal bowel resection for Crohńs disease. World J Surg 2003; 27: 1306-10.
[10]
Subramanian V, Saxena S, Kang JY, Pollok RC. Preoperative steroid use and risk of postoperative complications in patients with inflammatory bowel disease undergoing abdominal surgery. Am J Gastroenterol 2008; 103: 2373-81.
[http://dx.doi.org/10.1111/j.1572-0241.2008.01942.x]
[11]
Nguyen GC, Elnahas A, Jackson TD. The impact of preoperative steroid use on short-term outcomes following surgery for inflammatory bowel disease. J Crohn’s Colitis 2014; 8: 1661-7.
[http://dx.doi.org/10.1016/j.crohns.2014.07.007]
[12]
Kotze PG, Saab MP, Saab B, et al. Tumor necrosis factor alpha inhibitors did not influence postoperative morbidity after elective surgical resections in crohn’s disease. Dig Dis Sci 2017; 62: 456-64.
[http://dx.doi.org/10.1007/s10620-016-4400-2]
[13]
Ferrante M1, D'Hoore A, Vermeire S, et al. Corticosteroids but not infliximab increase short-term postoperative infectious complications in patients with ulcerative colitis. Inflamm Bowel Dis 2009; 15(7): 1062-70.
[http://dx.doi.org/10.1002/ibd.20863]
[14]
Zerbib P, Koriche D, Truant S, et al. Pre-operative management is associated with low rate of post-operative morbidity in penetrating Crohn’s disease. Aliment Pharmacol Ther 2010; 32: 459-65.
[http://dx.doi.org/10.1111/j.1365-2036.2010.04369.x]
[15]
2015 European Society of Coloproctology collaborating group. Risk factors for unfavourable postoperative outcome in patients with Crohn’s disease undergoing right hemicolectomy or ileocaecal resection. An international audit by ESCP and S-ECCO. Colorectal Dis 2017.
[http://dx.doi.org/10.1111/codi.13889]
[16]
Spinelli A, Allocca M, Jovani M, Danese S. Review article: optimal preparation for surgery in Crohn’s disease. Aliment Pharmacol Ther 2014; 40: 1009-22.
[http://dx.doi.org/10.1111/apt.12947]
[17]
Patel KV, Darakhshan AA, Griffin N, et al. Patient optimization for surgery relating to Crohn’s disease. Nat Rev Gastroenterol Hepatol 2016; 13: 707-19.
[http://dx.doi.org/10.1038/nrgastro.2016.158]
[18]
Scarpa M, Martinato M, Bertin E, et al. intestinal surgery for crohn’s disease: role of preoperative therapy in postoperative outcome. Dig Surg 2015; 32: 243-50.
[http://dx.doi.org/10.1159/000381885]
[19]
Lamore RF 3rd, Hechenbleikner EM, Ha C, et al. Perioperative glucocorticoid prescribing habits in patients with inflammatory bowel disease: a call for standardization. JAMA Surg 2014; 149: 459-66.
[20]
Magro F, Gionchetti P, Eliakim R, et al. Third European evidence-based consensus on diagnosis and management of ulcerative colitis. part 1: definitions, diagnosis, extra-intestinal manifestations, pregnancy, cancer surveillance, surgery, and ileo-anal pouch disorders. J Crohn’s Colitis 2017; 11: 649-70.
[21]
Harbord M, Eliakim R, Bettenworth D, et al. Third European evidence-based consensus on diagnosis and management of ulcerative colitis. part 2: current management. J Crohn’s Colitis 2017; 11: 769-84.
[22]
Øresland T, Bemelman WA, Sampietro GM, et al. European evidence based consensus on surgery for ulcerative colitis. J Crohn’s Colitis 2015; 9: 4-25.
[23]
Gionchetti P, Dignass A, Danese S. magro f, rogler f, lakatos p. 3rd european evidence-based consensus on the diagnosis and management of crohn’s disease 2016: part 2: surgical management and special situations. J Crohn’s Colitis 2017; 11: 135-49.
[24]
Bemelman WA, Warusavitarne J, Sampietro GM, et al. ECCO-ESCP consensus on surgery for crohn’s disease. J Crohn’s Colitis 2018; 12: 1-16.
[25]
Tzivanakis A, Singh JC, Guy RJ, et al. Influence of risk factors on the safety of ileocolic anastomosis in Crohn’s disease surgery. Dis Colon Rectum 2012; 55: 558-62.