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Mini-Reviews in Organic Chemistry

Author(s): Renato Dalpozzo*

DOI: 10.2174/1570193X16666181228100254

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The Synthesis and Use of BMS 204352 (MaxiPostTM)

Page: [67 - 73] Pages: 7

  • * (Excluding Mailing and Handling)

Abstract

MaxiPostTM is an interesting 3-fluorooxindole derivative, discovered in the late nineties of the last century as potassium channel opener. Since then, two different research fields were discovered: the discovery of new synthetic methods, especially asymmetric ones, and the in vitro and in vivo tests for its use as a drug for different diseases. This mini-review aims to summarize the state of art in both fields.

Keywords: Asymmetric synthesis, BMS204352, fluoroindoles, K-channel, MaxiPost, stroke.

Graphical Abstract

[1]
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