Author(s): Chuanhuan Chen, A. Xuejiao, Xia Li, Guoli Huang* and Bo Liu*
Page: [683 - 687] Pages: 5
* (Excluding Mailing and Handling)
We have developed a new method for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in good to excellent yields via phosphomolybdic acid (PMA)-catalyzed cyclocondensation of 2- aminobenzamides with aldehydes or ketones in N,N-dimethylformamide (DMF) at room temperature. The present method proves to be efficient in terms of short reaction time, high yield, simple workup and easy purification.
Keywords: 2, 3-dihydroquinazolinones, phosphomolybdic acid, 2-aminobenzamide, synthesis, ketone, aldehyde.
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