Current Stem Cell Research & Therapy

Author(s): Tapan Kumar Giri, Amit Alexander*, Mukta Agrawal, Swarnalata Saraf, Shailendra Saraf and Ajazuddin

DOI: 10.2174/1574888X13666180502103831

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Current Status of Stem Cell Therapies in Tissue Repair and Regeneration

Page: [117 - 126] Pages: 10

  • * (Excluding Mailing and Handling)

Abstract

Tissue engineering is a multi-disciplinary field such as material science, life science, and bioengineering that are necessary to make artificial tissue or rejuvenate damaged tissue. Numerous tissue repair techniques and substitute now exist even though it has several shortcomings; these shortcomings give a good reason for the continuous research for more acceptable tissue-engineered substitutes. The search for and use of a suitable stem cell in tissue engineering is a promising concept. Stem cells have a distinctive capability to differentiate and self-renew that make more suitable for cell-based therapies in tissue repair and regeneration. This review article focuses on stem cell for tissue engineering and their methods of manufacture with their application in nerve, bone, skin, cartilage, bladder, cardiac, liver tissue repair and regeneration.

Keywords: Tissue engineering, stem cell-based therapy, totipotent, pluripotent, mesenchymal stem cells, liver tissue regeneration.