Abstract

Background: Nanotechnology is steering mankind into new realms of efficient and miniature tools and gadgetry. The development of reliable, eco-friendly synthesis of nanomaterials is always an important aspect of nanotechnology. Silver nanoparticles have been used extensively as an antimicrobial agent and various products comprising of silver nanoparticles are accessible to the household.

Method: The aim of this study was to formulate an effective, stable nanoherbal antimicrobial cream and used topically in order to treat all type of skin infection. Therefore, here we have reported herbal based biosynthesized silver nanoparticles using Martynia annua (Bichu) herbal extract with an average particle size of 6 nm under ambient conditions. Structural investigations were examined by selected area electron diffraction (SAED) and powder XRD depicted perfectly crystalline nature of the particles.

Results: The obtained results confirmed that the Martynia annua (Bichu) extract is a good bioreductant for the synthesis of silver nanoparticles. The synthesized silver nanoparticles showed inhibition and had significant antibacterial activity against human pathogens gram-negative bacterial strains (Klebisella pneumoniase, Enterobcter cloacae, Pseudomonas aeroginosa and Escherichia Coli.)”.

Conclusion: These nanoparticles were employed as broad-spectrum antibiotics, after using in herbal based nanocream. Further, various physicochemical parameters of nanoherbal cream were measured.

Keywords: Herbal extract, nanomaterials, antimicrobial cream, biosynthesis, silver, nanotechnology.

Graphical Abstract