Letters in Organic Chemistry

Author(s): Motahareh Heidari, Mohammad Anary-Abbasinejad*, Dadkhoda Ghazanfari and Mohammad Reza Akhgar

DOI: 10.2174/1570178615666180102143215

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Synthesis of Polyfunctionalized Furans by Three-component Reaction Between Arylglyoxals, 1,3-Diketones and Isocyanides

Page: [773 - 777] Pages: 5

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Abstract

Three-component reaction between arylglyoxal monohydrates, isocyanides and 1,3- diketones in water is reported. This reaction provides a simple and efficient route for the synthesis of poly-functionalized furan derivatives. The reaction conditions and work-up procedure are simple and products were obtained in good yields.

Keywords: Arylglyoxal, three-component reaction, furan, isocyanide, 1, 3-diketones, aqueous media.

Graphical Abstract