Current Medicinal Chemistry

Author(s): Ian Scanlon, Panos Lehouritis, Ion Niculescu-Duvaz, Richard Marais and Caroline J. Springer

DOI: 10.2174/0929867033456837

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Gene Regulation in Cancer Gene Therapy Strategies

Page: [2175 - 2184] Pages: 10

  • * (Excluding Mailing and Handling)

Abstract

Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.

Keywords: transcriptional control, regulated expression, gdept, suicide gene