Background: The definition of the individual's molecular profile will promote a specific and tailored therapeutic approach for each patient. This method has found application in specific drug decision-making in the oncology field, but not for cardiovascular pathologies.
Objective: In this review, we describe some relevant molecular features of the cardiovascular disease in the context of personalized medicine, discussing how a multidisciplinary approach can favor its translation into daily patient management as a component of integrated care. Conclusion: Prevention of the Cardiovascular disease still lacks efficient models for personalized medicine, but the definition of the individual Metabolomics may represent a promising approach for filling this gap.Keywords: Cardiovascular diseases, genomics, metabolomics, innovation and communication technology, personalized medicine.