Recent developments of functionalization of C(sp3)-H bonds adjacent to oxygen of alcohols under metal-free conditions are summarized here. Alcohols are one of the most common and useful chemicals, so the direct functionalization of C(sp3)-H bonds adjacent to oxygen of alcohols is a promising direction in organic synthesis.
Keywords: Metal-free, alcohols, C(sp3)-H Bonds, C-C bond, organic synthesis, C-X bonds.