Abstract

Nanotechnology has been a promising therapeutic and scientific approach to effectively deal in healthcare with a potential to bring significant improvements in disease diagnosis and management. The existing drug regimen has become increasingly effective with the use of nanomedicines against many dreadful diseases especially AIDS. Nanomedicines have shown promising attributes such as slow and sustained release, nominal side effects, low toxicity, and increased concentration of the drug at the target site along with increased life-span of the drug. Still many challenges persist with regard to effective diagnosis and management of HIV infected patients considering the severity and complexity of the disease. The need is to develop effective nano-based regimens to diagnose, treat and manage AIDS by significantly improving the patient compliance along with reduced dosage frequency. The current review article has been designed to effectively address the state-of-the-art drug delivery strategies being implicated in the field of nanomedicine which could provide a better alternative for the existing HIV drug regimens offering more specificity, biocompatibility and biodegradability.

Keywords: AIDS, HIV, nanocarriers, nanoformulation, nanoparticles, nanotechnology, targeted delivery.

Graphical Abstract