Current Medicinal Chemistry

Author(s): Rajendra Pawar, Ariella Shikanov, Boris Vaisman and Abraham J. Domb

DOI: 10.2174/0929867043455981

DownloadDownload PDF Flyer Cite As
Intravenous and Regional Paclitaxel Formulations

Page: [397 - 402] Pages: 6

  • * (Excluding Mailing and Handling)

Abstract

Paclitaxel has been proven to be effective against different types of cancer. A delivery system loaded with paclitaxel at tumor site should provide a high local concentration of the drug detrimental to malignant cells, which prevents the re-growth and metastasis of tumor. In this review, paclitaxel formulations for systemic and for intratumoral administration are discussed.

Keywords: paclitaxel, delivery systems, polymers, intratumoral delivery, formulations