Current Bioinformatics

Author(s): Guojun Li, Qin Ma, Bingqiang Liu, Zheng Chang, Chuan Zhou and Zhenjia Wang

DOI: 10.2174/1574893611666160616130126

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An Insight into Species from Same Descendent Aspect and the Application into Clostridia

Page: [140 - 146] Pages: 7

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Abstract

Background: A phylogenetic tree which describes the evolutionary relationships among various species from a common ancestor is a fundamental concept in evolutionary biology. In recent years, a number of models of this tree structure have been proposed, mainly based on constructing a similar hierarchical structure or grouping together descendents with common ancestors.

Objective: We use vertices in an acyclic graph to represent different organisms, and seek those relatively important vertices of almost same descendents by tracing generations back of a set of vertices.

Method: We propose an algorithm for grouping based on previously theoretical analysis, which can alleviate the negative effects of incorrect initial central vertices and noisy frontier vertices by two strategies used in group merging step in our algorithm.

Results: The computational results in Clostridia show that our algorithm illustrates the data features better compared with the traditional hierarchy clustering method.

Keywords: Almost same descendents, differential vertex, natal vertex, pseudo-species.