Mini-Reviews in Medicinal Chemistry

Author(s): Wei Su, Zhaofeng Tang and Peiyuan Li

DOI: 10.2174/138955751610160503003937

Development of Arene Ruthenium Antitumor Complexes

Page: [787 - 795] Pages: 9

  • * (Excluding Mailing and Handling)

Abstract

The organometallic arene ruthenium complexes are rapidly advancing. In particular, the organoruthenium complexes of the type [(η6-arene)Ru(X)(Y)(Z)] have attracted increasing attention for their special structures and properties. This review is focused on the recent developments of [(η6- arene)Ru(X)(Y)(Z)]-typed complexes incorporating various biologically active ligands, which are important in the exploration of novel multi-targeted organometallic anticancer drugs.

Keywords: Anticancer agent, Arene, Biologically active ligands, Ruthenium.