Abstract

The effects of non-thermal intensity of microwave (NT MW)- treated physiological solutions (PS) on muscle contractility, ⁴⁵Ca uptake by muscle and muscle hydration of snail isolated heart in normal and K⁺-free PS were studied. The intra-cordial perfusion by NT MW-treated PS led to inhibition of heart beating with gradual decrease of the amplitudes of muscle contraction, the weakness of the Na⁺/K⁺ pump-induced transient inhibition of heart beating (TIHB), the inhibition of ⁴⁵Ca²⁺ uptake by muscle, the increase of intracellular cGMP contents and muscle dehydration. The obtained data serve as additional evidence for hypothesis that cell bathing aqua solution is a primary target for non-thermal effect of MW on cells and organisms.

Keywords: Non-thermal, MW, Heart muscle, Intracellular Ca²⁺, cGMP, Muscle hydration.

Graphical Abstract