Current Pharmaceutical Design

Author(s): D. Muriaux, J. L. Darlix and A. Cimarelli

DOI: 10.2174/1381612043382701

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Targeting the Assembly of the Human Immunodeficiency Virus Type I

Page: [3725 - 3739] Pages: 15

  • * (Excluding Mailing and Handling)

Abstract

In the rush to develop anti-viral drugs against the human immunodeficiency virus type I (HIV-1), all the steps of the viral life cycle are potential targets of therapeutic intervention. In this review, we will explore the recent advances on strategies that aim at obstructing the formation, the release and the infectivity of newly formed virion particles from HIV-1 infected cells.

Keywords: drugs, anti-viral approaches, virion assembly, hiv-1, retrovirus