Abstract

BINOL and its derivatives as a class of important and attractive compounds have been widely used in asymmetric synthesis. They could not only play as a part of chiral ligands, but also work well as organocatalysts. This review mainly focused on the recent progress in BINOL mediated asymmetric reactions including C-C bond forming reactions and C-hetero bond forming reactions.

Keywords: Asymmetric reaction, BINOL, chiral ligand, enantioselectivity, organocatalyst, stereoselectivity.

Graphical Abstract