Author(s): Ronghua Shi, Wensi Ai, Tao He, Xiaobo Ma, Shan Qian and Zhouyu Wang
Page: [720 - 726] Pages: 7
* (Excluding Mailing and Handling)
An efficient and simple way to synthesize N-(β-nitroalkyl) amides with broad substrate spectrum was developed. Various β-nitroarylethanols and nitriles were suitable substrate for the protocol. A series of N-(β-nitroalkyl) amides were synthesized through Ritter reaction and the yield is up to 95%.
Keywords: Alcohols, amides, carbocation, catalysis, nitriles.
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