CNS & Neurological Disorders - Drug Targets

Author(s): Bekir Kucuk, Yakup Cevik, Ugur Acar and Gungor Sobaci

DOI: 10.2174/1871527314666150821104800

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Therapeutic Potential of Erythropoietin in Retinal and Optic Nerve Diseases

Page: [1225 - 1234] Pages: 10

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Abstract

Recent studies have shown that, in addition to its well-known erythropoietic effects, erythropoietin has anti-inflammatory, neuroprotective, and neurotrophic effects in different tissues including the retina and optic nerve. In this review, we made a comprehensive search to define the therapeutic potential of erythropoietin in retinal and optic nerve diseases that lead to blindness.

Keywords: Erythropoietin, erythropoietic effect, neuroprotective, optic neuritis, optic nerve, retina.