Abstract

One-pot three component reaction of various types of aldehydes, dimedone, ammonium acetate and active methylene compounds was carried out in the presence of MCM-41 functionalized with B-F bonds nanostructured catalyst for the synthesis of polyhydroquinolines. MCM-41 was prepared by Sol-Gel method under mild conditions and B-F functionalized MCM-41 with various loading amounts of boron/fluoride were prepared and characterized by XRD, SEM, FT-IR, TEM and BET techniques. The results show that B-F functionalized MCM-41 with calcination temperature of 400ºC has the best catalytic activity. The catalyst is reusable many times with moderate decrease in activity.

Keywords: B-F functionalized MCM-41, mesoporous silica, nanostructured, polyhydroquinoline, reusability, solid acid catalyst.

Graphical Abstract