Abstract

The reactions of sulfur ylides with carbonyl, olefin or imine compounds named as the Corey- Chaykovsky, provide oxiranes, cyclopropane or aziridine, respectively. In this report, we try to introduce this important name reaction and highlight a comprehensive overview on the applications of this useful reaction in synthetic organic chemistry and total synthesis of natural products.

Keywords: Corey-Chaykovsky, epoxidation, dimethylsulfoxonium methylide, dimethylsulfonium methylide, organic and total synthesis.